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The gold nanoparticle solution is approximately 5.6 in pH and so the GSH binds to the gold nanoparticles in two places via the SH functional group from the glutamate moiety and the COO- functional group 55, 56

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But the good news is we have tested this treatment intravenously as well, and theres no sign of any toxicity, no sign of tumors at all after a year in mice, just blasting these genes but instead of three weeks which we do in the eye, blasting it for a year