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They can include: Your general health Your age Your physical conditioning Your lifestyle and physical activity level The medications you take Your weight The extent of the bone deformity The tears severity In most cases, milder injuries need less aggressive treatments than more moderate to severe tears or impingements

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Next to pharmacological or NAD + precursor modulators, it is possible to raise NAD + levels through exercise 302,306,307 , however, not all preclinical studies investigating exercise have linked increased NAD + levels to mitochondrial function