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A study in the Biochemical Journal showed that mice given IGF-1 LR3 experienced a 2.5x degree of anabolic muscle-building effects compared to mice receiving stand-alone IGF-1: The administration of insulin-like growth factor-I (IGF-I) via subcutaneously implanted osmotic pumps partially reversed a catabolic state produced by the co-administration of 20 micrograms of dexamethasone/day to 150 g male rats

The protective effect of KD and BHB it produces on DKD remains a subject of controversy

Scand J Clin Lab Invest 1992