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To understand the overall GLP-1 landscape, but also to get a good grasp of how Novo Nordisk and Eli Lilly really compete (and sometimes compliment each other), it was time to do a proper research piece on Eli Lilly

Typically, the concentration of carnitine in plasma is in the low M range (~4060), while tissue concentrations (taken here to approximate cytoplasmic concentrations) are in the low mM range (~15 mM) 26,27

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His colleague Shin-ichiro Imai, a professor of developmental biology at the Washington University School of Medicine who first met Sinclair in Guarentes lab, says Sinclair had a keen eye for capturing novel concepts and, based on that foundation, building new lines of research faster than anyone else. At the time, aging research, once considered a fringe science, was still in its infancy, but Sinclair was determined to propel it to legitimacy