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Systemic allergic reactions , whilst less common, may manifest as: Widespread urticaria (hives) raised, itchy welts that can appear anywhere on the body Generalised pruritus (itching) without visible rash Maculopapular rash flat red areas with small raised bumps Angioedema deeper swelling, particularly around the face, lips, or throat It is important to distinguish between common injection site reactions and genuine allergic responses

Your provider can discuss which option may be best for you

The key difference from phentermine is time

Retatrutide has data from thousands of trial participants over relatively short periods