semaglutide heart failure reduced ejection fraction New Science Suggests Improves CV Outcomes Beyond Weight Loss Oral Semaglutide Reduces Heart Failure

Yurkanin JP, Dean R and Wessells H

In preclinical models, catestatin exhibits anti-inflammatory, antihypertensive, and metabolic effects, and reduced circulating levels have been associated with hypertension, obesity, and insulin resistance ( Despite these associations, catestatin has received limited attention as a therapeutic candidate, in part because it does not conform neatly to classical endocrine paradigms and lacks a single dominant receptor target

Liver-selective THR agonists have thus emerged as promising agents capable of reversing hepatic steatosis and attenuating fibrosis

These injectable medications mimic a natural hormone that helps regulate appetite, blood sugar, and digestion