Two studies were published in the impactful New England Journal of Medicine [Reference Weghuber, Barrett and Barrientos-Prez1,Reference Arslanian, Hannon and Zeitler2], research motivated, as noted by the authors, in no small measure precisely because the currently approved medications for pediatric obesity and type 2 diabetes have proven to be limited in their effectiveness and fraught with adverse events [Reference Woodard, Louque and Hsia3]
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Louis, MO, USA) to localize nuclei and 5 M green 5-chloromethyl-fluorescein diacetate (CMFDA) (Invitrogen, San Diego, CA, USA), to detect GSH (specificity 95%) [31]
Rehman T, Shabbir MA, Inam-Ur-Raheem M, Manzoor MF, Ahmad N, Liu ZW, et al