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Metabolic Pharmaceuticals ultimately did not pursue Phase 3 trials for obesity, and the company's pipeline shifted toward other indications

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[2] [11] As of 2026, retatrutide has not received marketing authorisation from the Medicines and Healthcare products Regulatory Agency (MHRA) or the European Medicines Agency (EMA), and it remains an experimental compound available only within authorised clinical trial settings

It may also cause allergic reactions in some individuals