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The principle of using mAbs to increase IgG catabolism was also demonstrated in NHPs, when Nixon and colleagues at Dyax Corp used phage-display selected human IgG1 mAbs with high pH-independent affinity towards FcRn to reduce circulatory IgG without affecting albumin levels in NHPs [122]

June 12, 2025 5:16 View More Unlocking the Gut-Body Connection: The Surprising Links Between Digestion, Immunity & Mental Health In this podcast episode, host McCall McPherson is joined by two industry-leading guests in the microbiome and wellness space: Tina Anderson, CEO and Co-Founder of Just Thrive Probiotic & Antioxidant, and Kiran Krishnan, Microbiologist and Co-Founder of Microbiome Labs

NC, PM, JES, NJ and JT analyzed the results and corrected the manuscript