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Moreover, -blockers, especially those with vasodilatory properties, have been associated with antioxidant effects, potentially contributing to reducing oxidative stress markers

The synergy might arise from the combined action of GHK-Cu in stimulating glycosaminoglycan production, promoting collagen synthesis, and HA's role in reducing collagen degradation by scavenging reactive oxygen species and inhibiting matrix metalloproteinases

These effects were more dramatic with the balanced agonist and interestingly the beneficial metabolic effects occurred with no change in oral nutrient intake in peptide vs control groups

Funding The project was supported by National Natural Science Foundation of China (82000842)