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In a model of complete Achilles tendon transection in rats (Staresinic et al., 2003), BPC-157 administration resulted in significantly superior functional recovery compared to the control group, with improved collagen fiber organization on histological analysis
As is known, anti-GFAP is an astrocyte marker and anti-Iba-1 is a microglia marker
When GHK-Cu-injected chambers reproducibly contain more matrix and more cells than saline controls, the inference that the peptide accelerated the repair program is reasonably well supported within the model
A possible explanation for such different findings might be linked to the amount of coffee bioactives other than CGA provided with the two different coffee brews
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