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Topical WIN 55,212-2 confers long-term intraocular-pressure-independent neuroprotection in the DBA/2J mouse model of glaucoma

MOTS-c Mechanism and Dosing in the Stack Protocol MOTS-c (mitochondrial open reading frame of the 12S rRNA-c) is a 16-amino-acid peptide encoded in mitochondrial DNA, not nuclear DNAmaking it one of the few bioactive compounds produced directly by the mitochondria

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