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Yes, based on available evidence, concurrent use appears safe since semaglutide and glutathione operate through different biological pathways

Berberine also induces apoptosis via the mitochondrial pathway, promoting the release of cytochrome c from mitochondria, activating caspase-8, 9, and subsequent caspase-3 cascades, and triggering apoptosis by inhibiting the expression of Bcl-2 while increasing pro-apoptotic proteins (85)

Arch Med Sci 6:9095 Galloway SD, Craig TP, Cleland SJ (2011) Effects of oral: l-carnitine supplementation on insulin sensitivity indices in response to glucose feeding in lean and overweight/obese males