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Hum Reprod 39:21472159

6 12 A side effect of this design, however, is that gastric-emptying and postprandial-glucose benefits observed with CagriSema reflect both drugs, which is why isolating cagrilintides own gastric contribution is difficult

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In the TRIUMPH-1 Phase 3 trial, participants on the maximum dose of retatrutide (12 mg) lost an average of 28.3% of their body weight after 80 weeks, and up to 30.3% after 104 weeks in the study extension