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It can cause weight gain, especially around the belly and thighs, due to insulin resistance and hormone imbalances
Most PlexusDx patients find they naturally land in a 1,200 to 1,800 calorie range once their dose stabilizes, though individual variation is normal
At MC1R on melanocytes, MT-2 activates the cAMP-PKA-MITF-tyrosinase cascade, increasing eumelanin synthesis and skin pigmentation
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