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In addition, the concentration of NAD + metabolites significantly increased in the blood, skeletal muscle, and urine [120,130,131]

The human airway receives many insults from pathogens, pollen, dust, etc., every day that can contribute to illness, and people who have predispositions to deficiencies in mucus clearance are far more likely to experience an insult that tips their airway from maintaining homeostasis to cycling indefinitely between mucus hypersecretion, dehydration, plugging, and infection

If these are part of your routine, schedule them for times when your stomach is as empty as possible, ideally first thing in the morning before eating or at least 3 hours after a meal