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Patients on metformin immediate-release and another antihyperglycemic agent (N=229) and patients not on any antihyperglycemic agents (off therapy for at least 8 weeks, N=41) were randomized after a run-in period of approximately 10 weeks on metformin HCl immediate-release (at a dose of at least 1500 mg per day) in monotherapy

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Consistent use: Sticking with the routine for at least 34 months to move through full hair cycles