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This constriction will reduce blood flow by increasing the vascular resistance (both according to Poiseuilles law and because the viscosity of the blood increases at small vessel diameters due to interactions of the cells suspended in the blood with the capillary wall 36 )

Potential Drug Interactions If you are already taking medication for high blood pressure, adding a GLP-1 medication can create a double effect. Your existing blood pressure medication might become too powerful as you lose weight and as the semaglutide begins to lower your pressure naturally

This is an important area for future studies to explore