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Several FDA-approved medications, such as sorafenib, salazosulfapyridine (SAS), and acetaminophen, have been demonstrated to induce ferroptosis in a variety of cancerous and non-cancerous cell types by inhibiting the system Xc or GSH [130,131,132]
Metformin exerts anti-inflammatory and mucus barrier protective effects by enriching Akkermansia muciniphila in mice with ulcerative colitis
Since enzymes are one of the main costs in cell-free production, finding the minimum enzyme needed for the maximum production will make the pathway substantially efficient
doi: 10.1016/j.focha.2022.100087 115
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