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There is evidence from a previous meta-analysis that GLP-1RA confer a similar reduction in MACE in both sexes, whereas SGLT-2 inhibitors reduce the risk of MACE more in men than in women [31]

These drugs mimic the GLP-1 hormone, which helps regulate blood sugar levels, enhance insulin secretion, slow gastric emptying, and reduce appetite

GLP-1 medications provide gradual, sustainable results rather than instant changes

In people with type 2 diabetes or prediabetes, GLP1 activity can also improve glucose control, which may support broader metabolic goals when paired with nutrition, activity, and medical supervision