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doi: 10.1007/s12291-024-01191-2 102

Its structure allows for easy handling in various in vitro and in vivo research protocols

Stem-cell derived BBB models are the newest cell type model and have significantly higher expression of tight junction protein and transporters as well as TEER compared to hCMEC/D3 cells [118, 119]

Incompatible ingredients requiring separation include vitamin C (use morning versus evening rather than together), strong exfoliating acids (alternate nights rather than same routine), and retinoids (can be combined carefully but may increase irritation, alternating nights often works better)