glp-1 anesthesia One-Week Agonist Hold Not Enough Before Anesthesia? AAOMS may update anesthesia guide

Until those data arrive, a cautious, evidence aligned approach is recommended

& Bonkovsky, H

[DOI] [PMC free article] [PubMed] [Google Scholar] 54.Brilhante R.S.N., Sales J.A., Pereira V.S., Castelo D.D.S.C.M., de Aguiar Cordeiro R., de Souza Sampaio C.M., Paiva M.D.A.N., Dos Santos J.B.F., Sidrim J.J.C., Rocha M.F.G

Therefore, in line with 3 R animal experimental principles, we chose to conduct our proof-of-concept study directly in elephants since an in-target-species trial in a real-world setting provides an accurate reflection of the vaccines safety and immunogenicity, avoiding reliance on models that poorly recapitulate elephant immunology