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GLP-1RAs have multiple pleiotropic actions, as they bind to GLP-1 receptors expressed in many human tissues including the pancreas, kidneys, lungs, heart, brain, and gastrointestinal tract [5, 6]
125 These dietary practices could exacerbate the risk of malnutrition, sarcopenia, fatigue, delayed wound healing, and impaired immunity, particularly in cancer patients who are already at an increased age-associated risk for these conditions
the object of this invention is to provide a preparation method of high-purity L-carnitine, which is characterized in that to prepare L-carnitine with a purity being above 97%, wherein the content of D-carnitine is below 2%, by detecting and controlling the content of chiral material and chiral intermediate during the whole synthetic process which is started from S-epichlorohydrin, wherein the method include the following steps: the present invention provide a optically pure compound of formula (II) wherein R represents methyl, ethyl, isopropyl, butyl or benzyl, and X represents Cl or Br
