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HGH stimulates the liver to produce endogenous IGF-1, whereas IGF-1 LR3 bypasses the liver and acts directly on tissues, making it faster-acting and more targeted in its effects

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Bacterial species of Bacillus subtilis, Clostridium sporogenes, and Enterobacter aerogenes were grown together and the produced metabolites examined to analyze and predict the effects of the metabolites on insulin and proinsulin conversion