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But within the cosmetic-ingredient world, GHK-Cu is among the better-supported actives

Gonda, Y., Matsuda, A., Adachi, K., Ishii, C., Suzuki, M., Osaki, A., Mita, M., Nishizaki, N., Ohtomo, Y., Shimizu, T., Yasui, M., Hamase, K., & Sasabe, J

The efficacy of a second-generation derivative, omaveloxolone (RTA408), has recently been assessed in a preclinical model for diabetic chronic non-healing wounds [277] and, interestingly, omaveloxolone is now being tested in phase-II clinical trial for the Friedreichs ataxia (FRDA), a neurodegenerative condition in which NRF2 activation is suppressed [278, 279]

Atherosclerosis 1995