And then there are the therapists, social workers and case managersall of whom play a key role in recovery. Jeff especially appreciated how the team included him and Mary Lou in the process
They should be carefully administered to patients with risks of hypovolemia (older age, cardiovascular diseases, treatment with diuretics, liver cirrhosis with circulatory dysfunction)
Important next steps include exploratory early-phase trials to establish CNS penetrance, target engagement (CSF GLP-1/IGF-1), and downstream biomarkers such as MCP-1 and NfL, before larger efficacy studies can be justified

Key Facts and Rules Prioritize Protein: 1.21.6 g per kg of body weight per day (2530 g per meal) Eat Smaller, Balanced Meals: Reduces bloating, makes eating easier, and decreases nausea and discomfort Avoid Skipping Meals: Can lead to lower energy, insufficient protein, and muscle loss Prioritize Fiber: Promotes fullness and digestive health Moderate Fat Intake: Prioritize healthy fats and limit high-fat foods Maintain Hydration: 1.52 L water/day, sipping throughout the day Limited Processed Foods: Limit and avoid packaged, sugary, and fast foods Eat Until 80% Full: Prevents overeating and nausea Ideal Eating Schedule Breakfast: 8 AM Lunch: 121 PM Snack: 34 PM Dinner: 67 PM 7-Day Semaglutide Meal Plan The following meal plan provides your body with essential nutrients to maintain optimum health while taking semaglutide