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For example, the combination of 2-deoxyglucose (glycolytic inhibitor), metformin (glycolytic inhibitor), compound C (an AMPK inhibitor), MLN128 (mTOR1 inhibitor), and other glutamine metabolism inhibitors have shown synergistic antitumor effects in some cancer models (Elgogary et al., 2016
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Int J Biol Macromol 307(Pt 2):142015 Zhra M, Elahi MA, Tariq A, Abu-Zaid A, Yaqinuddin A (2025) Sirtuins and gut microbiota: dynamics in health and a journey from metabolic dysfunction to hepatocellular carcinoma
Kania-Dobrowolska M, Baraniak J
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