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The exact in-use period depends on the bacteriostatic water vehicle and any compounding-pharmacy-specific guidance on the vial

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When used concurrently with insulin or insulin secretagogues such as sulfonylureas or meglitinides, the risk of hypoglycemia may be increased, particularly during the initiation of therapy or following dose escalations

Their proposed mechanisms of action include the promotion of angiogenesis, modulation of inflammatory cascades, and enhancement of tissue repair through multiple cellular pathways