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[] Controlled The randomized, double-blind, and placebo-controlled 12-week study evaluating the effectiveness of NAC in treating OCD showed a progressive and continuous reduction in the severity of disease symptoms in 19 patients (age: 2344) following treatment with NAC (titrated from 600 mg daily to 2.4 g daily at week 3) compared to the placebo ( n = 20)

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Glucuronidation also contributes to ochratoxin A detoxification, so UGT variants may have an overlapping impact across several mycotoxins.[ref] Related article: Glucuronidation: UGT Genetic Variants, Detoxification, and Hormone Balance Patulin and glutathione-dependent pathways: Patulin, a mycotoxin most commonly found in moldy apples and apple juice, binds to thiol groups in glutathione, depleting this key intracellular antioxidant and triggering oxidative stress and mitochondrial dysfunction

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