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GLP-1 receptor agonists are medications that mimic this hormone amplifying its effects

morning dosing helps in trials Category Cardiovascular Examples reported Heart rate increase of 5-10 bpm typical at 0.5 mg, blood pressure rise mostly at 1.0 mg Comment Main reason the US and EU programs stalled Category Psychiatric Examples reported Anxiety, irritability, mood changes Comment Trials excluded active psychiatric disease

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--- In just five years, GLP-1s have gone from niche second-line agents to the dominant therapy class in type 2 diabetes