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When neurological symptoms are present, more intensive treatment is required: 1 mg hydroxocobalamin on alternate days until no further improvement occurs, followed by maintenance therapy every two months

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In a phase II trial, participants with obesity were randomly assigned to various doses of retatrutide from 14 , 8, or 12 mg or a placebo for 48 weeks [19]

While injectable BPC-157 has been widely studied for tissue repair, the oral formulation offers unique advantages by delivering the peptide directly to the gastrointestinal tract, where it can exert both local and systemic healing effects