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Researchers using AOD-9604 beyond that window are operating in an evidence gap

5.5 Current status of research into the endothelial glycocalyx in sepsis Endothelial dysfunction and glycocalyx damage have become a focus of sepsis research, and markers of glycocalyx degradation are being identified

Its use as a solution for injection of 1% provides a calming and muscle relaxant effect by reducing the excitation of the central nervous system

However, many candidates met other criteria for eligibility: 53.2% had a history of psoriasis affecting high-impact sites, and 55.2% reported prior but not current use of topical therapy [28]