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We are encouraged by the robust reductions in liver fat content and abdominal adipose tissue observed with all three doses of tirzepatide in this population of adults with type 2 diabetes and elevated liver fat content. SURPASS-3 was a 52-week, multi-center, randomized, phase 3, open-label trial evaluating the efficacy and safety of tirzepatide compared to titrated insulin degludeci in adults with type 2 diabetes who have inadequate glycemic control on stable doses of metformin with or without an SGLT-2 inhibitor

These include lifestyle modification requirements (69%), trialing lower-cost medications first (63%) and limiting therapy duration (63%)

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The study was comprehensive, involving 751 participants over 72 weeks to measure results accurately