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upon mitochondrial damage, PINK1 accumulates on the mitochondrial outer membrane to attract E3 ubiquitin ligase parkin for clearance of damaged mitochondrial through autophagy (Pickrell and Youle, 2015)

In PsA patients, WAT localized in entheses-associated regions like the retrocalcaneal fat pad, shows impaired lipolysis, reduced adiponectin secretion, and increased fatty acid -oxidation, possibly emphasizing its pathological significance [48,49,50]

'Ozempic tongue' is not an official medical diagnosis, but it has become a popular term among GLP-1 users describing an unexpected change in how food tastes