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Video: Indicaties en werkzaamheid: Behandeling van obesitas: Tijdens het klinische onderzoek in fase II verloren patinten in de hoogste doseringsgroep (12 mg) gemiddeld 24,2% van hun gewicht na 48 weken, en sommige patinten verloren meer dan 30%

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GLP-1R is expressed on cocaine- and amphetamine-regulated transcript (CART)/proopiomelanocortin (POMC) neurons in the hypothalamus, which regulate satiety and termination of meals [40]