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New indications, such as cardiovascular risk reduction and obstructive sleep apnea, are redefining the value proposition of these drugs and influencing both prescribing patterns and reimbursement decisions

In consideration of the semaglutide-related GI AEs, treatment with GLP-1 RAs should begin with a structured dose-escalation schedule aimed at minimising these effects [64,65,66]

Because of trademark issues, physiologists typically prefer the name epinephrine for the hormone

3 An association of centrofacial lentiginosis and giant nevus spilus developing on the left side of the upper back in a dermatomal distribution has been reported in a child