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To better understand the role of W33 in small-molecule agonist binding to GLP-1R, we generated the cryo-EM structure of a PF-06882961 analog (PF-06883365) bound to human GLP-1R (Fig

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Anubis is a compromise

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Formycin A (an analogue of adenosine) is a well-known inhibitor of hexameric PNPs (Bzowska et al

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