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After reviewing 25 randomized controlled trials, we found that: 56% of nutrition interventions delivered in primary care were cost-effective 20% were moderately cost-effective The strongest economic outcomes were observed for telehealth and diabetes-focused interventions Behind these findings was an extensive process of harmonising health economic data across countries, calculating Incremental Net Benefit (INB), and performing meta-analysis and sensitivity analyses to produce robust, comparable evidence for decision-making
Opioids Opioids mask pain through central nervous system effects but carry risks of tolerance, dependence, overdose, and paradoxical opioid-induced hyperalgesia
Lean mass versus function An increase in lean body mass does not necessarily produce meaningful improvements in strength, mobility, injury recovery, or health
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