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Tirzepatide is a once-weekly dual GIP and GLP-1 receptor agonist that produced mean weight reductions of 15.0%, 19.5%, and 20.9% with 5 mg, 10 mg, and 15 mg doses respectively over 72 weeks in adults with obesity, versus 3.1% with placebo, in the SURMOUNT-1 trial [4]

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Biochimica et Biophysica Acta - General Subjects , 1830(5), 31433153

In elderly patients with diabetes, the initial dosing, dose increments, and maintenance dosage should be conservative to avoid hypoglycemia [see WARNINGS AND PRECAUTIONS , ADVERSE REACTIONS , and Clinical Studies ]