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In contrast, those who switched to placebo regained significant weight, ending the study with only a -9.9% change from baseline

If their body mass index is in the 85th percentile or above and they have at least one chronic condition (known as comorbidity in medicine) such as high blood pressure or Type 2 diabetes, they can qualify

J Clin Invest 122:15741583 McGill MR, Cao M, Svetlov A, Sharpe MR, Williams CD, Curry SC, Farhood A, Jaeschke H, Svetlov SI (2014a) Argininosuccinate synthetase as a plasma biomarker of liver injury after acetaminophen overdose in rodents and humans

Labs showed mitochondrial dysfunction, high inflammation, and low magnesium levels