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True recovery requires a holistic approach that includes aggressive pacing to prevent post-exertional malaise, targeted nervous system regulation, environmental detoxification, and personalized medical care

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Szabo, G., Thursz, M

This NO-loaded form of hemoglobin can release NO, which is then transferred to targets such as Band 3 on the erythrocyte membrane or to thiol-containing molecules in the endothelium ( SNO derived from erythrocytes also plays a key role in communicating with endothelial cells during hypoxia, promoting vasodilation through NO release