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Interestingly, the cavity corresponding to Cavity II in the ghrelin receptor is closed in the motilin receptor, and this closure is primarily attributed to Phe173 4.60 and Leu249 5.40 in the motilin receptor, corresponding to Ile178 4.60 and Val214 5.40 in the ghrelin receptor (Figures 4B,C)

Yan C, Chen J, Wang C, Yuan M, Kang Y, Wu Z, et al

If discomfort occurs, reducing frequency or seeking professional advice may help

Funding This work was financially supported by the National Natural Science Foundation of China (82100447, 81602327), the Fundamental Research Funds for the Central Universities (2242023K40035), and the Zhishan Scholars Programs of Southeast University (2242021R41070)