However, as with any combination therapy, potential side effects, dosing regimens, and specific patient needs must be carefully considered
Severe thiamin deficiency, which is rare in industrialized nations, except in patients with chronic alcoholism, HIV-AIDS, or gastrointestinal conditions that impair vitamin absorption (23), results in the condition called beriberi, of which there are many forms that involve neurological symptoms
Furthermore, platinum-based drugs elevate ROS levels that promote PCD
1 H NMR (300 MHz, DMSO) 8.26 (d, J = 7.6 Hz, 1H), 7.45 7.34 (m, 9H), 7.25 (d, J = 1.4 Hz, 1H), 7.13 7.03 (m, 6H), 7.03 6.95 (m, 1H), 6.70 6.61 (m, 1H), 4.49 (q, J = 6.9 Hz, 1H), 3.54 (s, 3H), 3.52 (d, J = 5.9 Hz, 1H), 2.82 (dd, J = 6.7, 3.4 Hz, 2H), 1.35 (s, 9H)