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Asparaginase therapy in patients with acute lymphoblastic leukemia: expert opinion on use and toxicity management

As Yuval Ramot from the Department of Dermatology at Hadassah Medical Center notes: "Almost all local reactions to subcutaneously administered biological agents can be prevented by changing the injection techniques, patient education, and training." While most redness and warmth from injections resolve within 24 to 48 hours, mistakes in technique can prolong these symptoms

From 2004 to 2009, an analysis of the database revealed a six-fold increase in pancreatitis incidents linked to the DPP-4 inhibitor sitagliptin and the GLP-1 mimetic exenatide, the first two GLP-1-based medications marketed in the US [51]

Hepatology 52 , 18361846 (2010)