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Melanotan II + PT-141 is sold strictly for laboratory and research purposes and is not approved by the FDA or other regulators for human use

Animal model research has demonstrated that intranasal NPY administration reverses anxiety and depressive behavior in PTSD models

If your TDEE is low and a 12.5% deficit would put your target below 1,200 kcal for women or 1,500 kcal for men, the calculator raises it back to that minimum