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Int J Neuropsychopharmacol 14(1):123130 Godlewska BR, Near J, Cowen PJ (2015) Neurochemistry of major depression: a study using magnetic resonance spectroscopy

Maintenance dosing means taking a lower dose regularly to keep B12 levels up, used for long-term prevention

What lipotropic injections plausibly contribute is more modest and more defensible: correction of real deficiencies, a tolerable non-stimulant option for patients who cannot or will not take prescription weight loss medication, and a recurring touchpoint that keeps patients engaged with a supervised program

Larger, higher-quality trials focused on B12 alone simply dont show consistent, clinically meaningful fat loss