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Description

5), S42S47 (2001)

nausea limits dose escalation | | PT-141 Monotherapy | MC3R, MC4R (selective

VacA insertion facilitates mitochondrial depolarization, swelling, and the release of pro-apoptotic factors such as apoptosis-inducing factor (AIF) and cytochrome c ( Listeria monocytogenes , an intracellular pathogen, secretes listeriolysin O (LLO), a cholesterol-dependent cytolysin that destabilizes host membranes, including mitochondrial membranes (Li et al., 2021)

While reported to be most common in Caucasians [5, 16], cases presenting in dark-skinned individuals may be misinterpreted as physiologic pigmentation