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4.1
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Description

Both legal authorities and medical ethics counsel restraint

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The original authors interpreted the carry-over as evidence of programming a chronobiological system

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In female mice, the incidences of pituitary gland adenomas and mammary gland adenocarcinomas and adenoacanthomas were increased at dietary doses of 3 to 30 mg/kg/day (0.1 to 0.9 times human exposure at MRHD based on AUC and 0.5 to 5 times the MRHD based on mg/m2)

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