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These include: Nause Diarrhea Vomiting Constipation Reduced appetite Abdominal discomfort Possible unusual skin sensations, also called dysesthesia Serious GLP-1 Side Effects Most GLP-1 side effects are mild, but rare, serious problems can happen

The article states that GLP-1 receptor agonist patches do not currently exist as an FDA-approved treatment for weight management or diabetes, and that no patch formulation has completed Phase 3 trials for either use