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Given the molecular complexity that characterises cancer development and progression, it is not easy to classify a factor like Nrf2 as positive or negative in the disease outcome

in Spain, its current prevalence ranges between 2833%11,12 and it is a recognized as a cardiovascular risk factor and increases the mortality in this population.1315 Furthermore, in patients with DM2 and advanced CKD there are limitations in the prescription of certain antihyperglycemic drugs (e.g., metformin or sulfonylureas) and there is an increased risk of hypoglycemia with antihyperglycemic treatment,16 a complication that is associated with increased cardiovascular risk17 and hinders the achievement of glycemic control targets

Last updated on 10/18/23

Results vary by individual based on genetics, training, nutrition, and adherence